Top 2 Bedroom Hotels in Key West

We checked thousands of reviews on and to find the best hotels for your stay
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Welcome to the tropical paradise of Key West, where pristine beaches and vibrant culture converge to create a memorable vacation experience. As you plan your visit to this picturesque island in the Florida Keys, consider the allure of 2 bedroom hotels in Key West for a spacious and comfortable stay. Opting for a 2 bedroom hotel offers the perfect blend of privacy and convenience, ideal for families, groups of friends, or those seeking extra space to unwind after a day of exploration.

Discover a diverse selection of 2 bedroom hotels in Key West, ranging from charming boutique properties to luxurious resorts with breathtaking ocean views. These accommodations provide a home away from home, complete with separate living areas, kitchen facilities, and the added flexibility of multiple bedrooms for your comfort. Whether you prefer a cozy boutique hotel in Old Town or a lavish oceanfront resort along the famous Duval Street, Key West offers a myriad of options to suit your preferences.

Immerse yourself in the laid-back island lifestyle of Key West while enjoying the comfort and convenience of 2 bedroom hotels that cater to your every need. From convenient amenities such as pool access and on-site dining options to personalized concierge services, these accommodations elevate your vacation experience in the very heart of this vibrant destination. Let the allure of 2 bedroom hotels in Key West enhance your stay and create lasting memories of your tropical escape.

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Our Top 8

(Sorted by rating & number of reviews)

1. The Inn On Fleming
2. Parrot Key Hotel & Villas
3. Hyatt Vacation Club At Beach House Hotel
4. The Reach Key West, Curio Collection By Hilton Hotel
5. The Gardens Hotel
6. Sunset Key Cottages
7. Santa Maria Suites Resort
8. The Marquesa Hotel

Luxury Waterfront 2 Bedroom Hotels in Key West

Check Availability

Key West
Mar 17, 2026 - Mar 18, 2026

The Inn On Fleming

9.1

Good

(489 Reviews)

+ 103 photos
Discover a hidden gem at The Artist House on Fleming, a charming guesthouse housed in a meticulously restored Victorian mansion in the heart of Key West. The 2 bedroom suites feature eclectic decor, original artwork, and a cozy ambiance that reflects the artistic spirit of the island. Unwind in the lush garden courtyard, mingle with fellow guests during the daily wine and cheese reception, and experience the unique blend of art and hospitality at this historic property.
Address: 1016 Fleming St.
Rating: Good 9.1 (489 Reviews)
Rooms: 9
Price: From 347$

Parrot Key Hotel & Villas

8.4

Good

(2879 Reviews)

+ 247 photos
Escape to a tropical paradise at Parrot Key Hotel & Villas, a family-friendly resort with spacious 2 bedroom villas overlooking the serene waters of the Gulf of Mexico. The colorful villas feature modern amenities, private balconies, and easy access to the waterfront pool and sandy beach. Families can enjoy complimentary shuttle service to Duval Street, on-site water activities, and a relaxing atmosphere perfect for creating lasting memories together.
Address: 2801 N Roosevelt Blvd
Rating: Good 8.4 (2879 Reviews)
Rooms: 148
Price: From 197$

Historic Boutique 2 Bedroom Hotels in Key West

Immerse yourself in the rich history and charm of Key West with our selection of boutique 2 bedroom hotels, each offering a unique blend of historic architecture and modern comforts. These boutique properties capture the essence of Key West's vibrant culture, providing a personalized and intimate experience for guests looking to explore the island's storied past. From quaint guesthouses in Old Town to historic landmarks transformed into boutique hotels, these accommodations offer a glimpse into Key West's colorful past while providing modern conveniences.

Hyatt Vacation Club At Beach House Hotel

9.0

Good

(601 Reviews)

+ 44 photos
Experience the ultimate family getaway at Hyatt Residence Club Key West offering 2 bedroom suites with modern furnishings, fully equipped kitchens, and easy access to the beach. The resort-style amenities include a heated outdoor pool, water sports rentals, and a kids' club, ensuring that every member of the family has a memorable vacation. Indulge in casual dining at the on-site restaurant or explore the nearby attractions and outdoor adventures that Key West has to offer.
Address: 5051 Overseas Hwy
Rating: Good 9.0 (601 Reviews)
Rooms: 74
Price: From 340$

The Reach Key West, Curio Collection By Hilton Hotel

7.1

Good

(336 Reviews)

+ 137 photos
Situated along a pristine stretch of white sandy beach, The Reach Key West boasts 2 bedroom suites with modern coastal decor and breathtaking ocean views. Guests can relax by the oceanfront pool, savor fresh seafood at the beachside restaurant, or embark on a sunset cruise from the private marina. The hotel's impeccable service and upscale amenities ensure a luxurious stay in Key West.
Address: 1435 Simonton Street
Rating: Good 7.1 (336 Reviews)
Rooms: 150
Price: From 279$

Family-Friendly 2 Bedroom Hotels in Key West

Plan a memorable family vacation in Key West with our selection of family-friendly 2 bedroom hotels, catering to the needs of parents and children alike. These accommodations offer spacious suites, kid-friendly amenities, and convenient proximity to family-friendly attractions, ensuring a fun and stress-free stay for guests of all ages. Whether you're seeking a resort-style experience with on-site activities or a cozy guesthouse with a welcoming atmosphere, these hotels provide the perfect home base for your family adventures in Key West.

The Gardens Hotel

9.6

Good

(145 Reviews)

+ 158 photos
Step back in time at The Gardens Hotel, a historic mansion turned boutique hotel featuring lush tropical gardens and elegant 2 bedroom suites. This luxury retreat exudes Southern charm and sophistication, with colonial-style architecture, antiques, and modern amenities. Relax in secluded courtyards, savor breakfast under the canopy of majestic trees, and unwind in the serene ambiance of this hidden gem in the center of Old Town.
Address: 526 Angela Street
Rating: Good 9.6 (145 Reviews)
Rooms: 22
Price: From 309$

Sunset Key Cottages

9.2

Good

(108 Reviews)

+ 186 photos
Experience refined luxury at Sunset Key Cottages, nestled on a private island just off the coast of Key West. The 2 bedroom cottages offer a serene retreat with elegantly appointed interiors, private pools, and stunning sunset views over the Gulf of Mexico. Indulge in gourmet dining at the on-site restaurant or enjoy a rejuvenating spa treatment surrounded by lush tropical gardens.
Address: 245 Front St
Rating: Good 9.2 (108 Reviews)
Rooms: 40
Price: From 760$

Santa Maria Suites Resort

9.3

Good

(668 Reviews)

+ 106 photos
Unwind in luxury at Santa Maria Suites Resort, a family-friendly retreat offering 2 bedroom suites with fully equipped kitchens, separate living areas, and private balconies or patios. The resort's lush tropical gardens, sparkling pool, and complimentary breakfast set the stage for a relaxing and enjoyable family vacation in Key West. Explore the nearby attractions, including beaches, museums, and exciting water sports activities, all within easy reach of this upscale resort.
Address: 1401 Simonton St
Rating: Good 9.3 (668 Reviews)
Rooms: 35
Price: From 190$

The Marquesa Hotel

9.5

Good

(83 Reviews)

+ 209 photos
Experience the allure of Key West's historic district at The Marquesa Hotel, a boutique oasis offering spacious 2 bedroom suites in a tranquil garden setting. The hotel's Victorian-inspired architecture, luxurious furnishings, and exceptional service create a refined yet welcoming atmosphere for discerning travelers. Explore the vibrant neighborhood, dine at award-winning restaurants nearby, and immerse yourself in the vibrant art and culture scene of Key West.
Address: 600 Fleming Street
Rating: Good 9.5 (83 Reviews)
Rooms: 44
Price: From 440$